tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate
1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-diMethylethyl ester
CAS: 631912-39-5
Molecular Formula: C19H27BN2O4
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate - Names and Identifiers
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C19H27BN2O4 |
| Molar Mass | 358.24 |
| Storage Condition | 2-8°C |
tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate - Introduction
Acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1 1-diMethyl ester is an organic compound with the chemical formula C15H22BN3O4. It is a white crystalline solid with good solubility and is soluble in common organic solvents such as methanol, dimethylformamide and N,N-dimethylformamide.
The compound is commonly used in protecting group reactions in organic synthesis, has stability and selectivity, and can protect amino groups (such as aniline) or hydroxyl groups. It has a wide range of applications in pharmaceutical chemistry, simple synthesis and chiral synthesis.
The preparation of acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1, 3,2-dioxolan-2-yl)-, 1,1-dimethylethyl ester is usually carried out in two steps. First, benzimidazole is esterified with tert-butyl carbonate to obtain 1-Boc-6-methylbenzimidazole. This is then subjected to a condensation reaction with 4,4, 5,5-tetramethyl -1,3, 2-dioxolene borate (abbreviated as B2pin2) under basic conditions to yield the desired product.
Regarding safety information, acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1-diMethyl ester has low toxicity, but basic laboratory operation specifications should be followed, protective measures should be taken, and skin contact and inhalation should be avoided. Personal protective equipment such as chemical protective gloves and goggles should be used if required. At the same time, storage should avoid contact with oxidants, stored in a dry, cool place.
The compound is commonly used in protecting group reactions in organic synthesis, has stability and selectivity, and can protect amino groups (such as aniline) or hydroxyl groups. It has a wide range of applications in pharmaceutical chemistry, simple synthesis and chiral synthesis.
The preparation of acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1, 3,2-dioxolan-2-yl)-, 1,1-dimethylethyl ester is usually carried out in two steps. First, benzimidazole is esterified with tert-butyl carbonate to obtain 1-Boc-6-methylbenzimidazole. This is then subjected to a condensation reaction with 4,4, 5,5-tetramethyl -1,3, 2-dioxolene borate (abbreviated as B2pin2) under basic conditions to yield the desired product.
Regarding safety information, acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1-diMethyl ester has low toxicity, but basic laboratory operation specifications should be followed, protective measures should be taken, and skin contact and inhalation should be avoided. Personal protective equipment such as chemical protective gloves and goggles should be used if required. At the same time, storage should avoid contact with oxidants, stored in a dry, cool place.
Last Update：2024-04-09 21:11:58
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Product Name: 1H-BenziMidazole-1-carboxylic acid, 6-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-diMethylethyl ester Visit Supplier Webpage Request for quotation
CAS: 631912-39-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 631912-39-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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tert-Butyl 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole-1-carboxylate
BATHOPHENANTHROLINEDISULPHONIC ACID DISODIUM SALT
Kaempferol 3-O-robinoside
BATHOPHENANTHROLINEDISULPHONIC ACID DISODIUM SALT
Kaempferol 3-O-robinoside